c-Src was overactivated in lung adenocarcinomas relative to that in paracancerous tissues (Additional file 3: Table S2 and Fig. 1b), and this overactivation was tightly correlated with decreased E-cadherin expression as determined by a protein antibody microarray (Additional file 5: Figure S1A and Fig. 1b). This evidence concerns the gene SRC and lung adenocarcinoma.