Canonical pathways inLSalso confirmed MMR involvement in syndrome, while otherpathways included colorectal cancer metastasis signaling andovarian cancer signaling (Figure 2).While the analysis of upstreamregulators of the target molecules yield to be the MBD4, PTTG1,CHI3L1, TP53,and MYC (Table 2 shows complete list). The gene discussed is MBD4; the disease is colorectal cancer.