CGAS and infection: Flowcytometric data ascertained significant decrease in MHCII expression by IFNɣ treatment in cells with SBR-LD infection compared with SBR-LD infection in wild-type RAW 264.7 ISG reporter cells but not in ISG-KO-cGAS cells, at 18 hpi (3 fold; P < 0.0001) (Fig. 6E).