Assuming that these SNPs are the causal variants, the observed effect size estimates may indicate potential escape from XCI for FHL1 and SRPX. Interestingly, for height (effect size ratio = 2.12, SE = 0.35; PXWAS, combined = 1.9 × 10–37) and BMR (effect size ratio = 3.26, SE = 1.21; PXWAS, combined = 6.6 × 10–12) the results for the SNP rs35318931 in the SRPX gene were indicative of DC. Here, SRPX is linked to dyskeratosis congenita.