In our previous study, CHST15, a specific enzyme that biosynthesizes chondroitin sulfate-E (CS-E), which is highly expressed in human pancreatic cancer cells, was found to be a key player in tumor growth, and the effects of STNM01 on tumor cell proliferation in vitro and growth in vivo were demonstrated [4]. Here, CHST15 is linked to familial pancreatic carcinoma.