In agreement with the above evidence, we previously demonstrated that high CHST15 expression, which is responsible for the biosynthesis of sulfated CS-E, may represent a potential predictive marker of OS in patients with pancreatic cancer following surgical resection [64], and that STNM01, a CHST15 siRNA, successfully inhibited pancreatic tumor growth in xenograft experiments using the RNAi strategy, as shown in Figure 2 [4]. The gene discussed is CHST15; the disease is pancreatic neoplasm.