TNF and psoriasis: Among keratinocyte-derived AMP, the catheledicin LL37 has a pivotal role in the development of psoriasis, through its capacity to activate pDC and myeloid DC (mDC), with consequent initiation of the adaptive immune phase [6,7] and activation of the IL-23–T helper (Th)17/Th22 and IL-12-IFN-γ/TNF-α axes [2].