Moreover, DHA significantly decreased the protein expression levels of PU.1 (Spi-1 proto-oncogene) and AHR (Aryl hydrocarbon receptor) in the LPMCs of the OXA colitis model (Figure 3B) and decreased the protein levels of T-bet and RORγt in the TNBS colitis model (Figure 3D). This evidence concerns the gene SPI1 and colitis.