Festen and colleagues in their meta-analysis of two genome-wide association studies GWAS also identified the genes interleukin 18 receptor accessory protein (IL18RAP); phosphatase, non-receptor type 2 (PTPN2); T cell activation RhoGTPase activating protein (TAGAP) and pseudouridine synthase 10 (PUS10) as having shared risk loci for CD and coeliac disease [211]. Here, IL18RAP is linked to celiac disease.