SCN1A and Dravet syndrome: Experimental models of DS, including mice lacking a functional copy of Nav1.1 (Scn1a+/- mice) (Mistry et al., 2014; Ogiwara et al., 2007; Yu et al., 2006) and neurons generated from induced pluripotent stem (iPS) cells derived from DS patients (Liu et al., 2013; Sun et al., 2016), have provided important insights into the cellular and circuit basis of this disorder.