These included nine genes previously reported to be of significance in GBM, such as IL1B,23 SERPINE1,24 TFPI2,25 LGALS1,26 CD63,27 VIM,28 CSF3,29 TIMP130 and S100A6,31 as well as three genes (AKR1B1, MT2A and UBC) not yet reported to have an effect in GBM cells. The gene discussed is SERPINE1; the disease is glioblastoma.