NUCLEOLIN and cancer: For example, LYAR, a zinc finger protein, more frequently found in the nucleolus for promoting cell growth by preventing nucleolin self‐cleavage,44 has also been associated to cytoplasmic ribosomes in human cancer cells.42 From the cytoplasmic compartment, Lyar protein dissociates from the cytoplasmic 60S ribosomial subunit shuttling rapidly to the nucleolus for absolving nuclear functions.