The anti‐tumoural role of NKILA, a cytoplasmic NF‐κB interacting long non‐coding RNA, has been recently demonstrated in multiple cancers, including those of the breast.25, 26, 27 Here, we elucidate the NF‐κB/NKILA pathway in relation to EZH2, an immediate regulator of NF‐κB activity in cancer cells. Here, NFKB1 is linked to cancer.