The SUMO-1 conjugates, SUMO-1, TP53INP1, and p53 proteins were then measured by western blotting, and we observed significantly increased SUMO-1 conjugation, TP53INP1, and p53 protein expression in the cataract group while the protein expression of free SUMO-1 did not significantly differ between the two groups (Figures 1(b)–1(d)). The gene discussed is TP53; the disease is cataract.