Another meta-analysis performed by our group including 25 studies clarified the peripheral blood inflammatory cytokine profile in ALS, which revealed elevated blood TNF-α, TNF receptor 1, IL-6, IL-1β, IL-8, and vascular endothelial growth factor levels in patients with ALS relative to control subjects [10]. The gene discussed is CXCL8; the disease is amyotrophic lateral sclerosis.