FMO5 and amyloidosis: To examine whether oxidative stress contributes to the process of AApoAII amyloidosis, R1.P1-Apoa2c mice were administered the ROS scavenger tempol (1 mM) or the NADPH oxidase inhibitor apocynin (1.5 mM) in drinking water for 8 or 12 weeks beginning at 8 weeks of age.