Univariate Cox regression analysis revealed that vascular invasion, tumor size, number of tumors, BCLC stage, TNM stage, and TFAP4 expression were all strongly correlated with OS rates (Table 2), while gender, vascular invasion, tumor size, number of tumors, AFP, BCLC stage, TNM stage, and TFAP4 expression were strongly correlated with DFS (Table 3). This evidence concerns the gene TFAP4 and neoplasm.