Overexpression of the cancer progression-associated miR-146a in MSC after incubation with exosomes from the MM cell lines RPMI 8226, OPM-2, LP-1, and U266 induces secretion of IL-6, CXCL1, IP-10 (interferon gamma-induced protein 10), and CCL5 and enhances tumor cell survival and migration [91]. The gene discussed is CCL5; the disease is cancer.