EIF4E and Miyoshi myopathy: A study that investigated how BM-MSC-MV from normal subjects and MM patients affect the phenotype, translation initiation, and MAPK signalling in five MM cell lines (U266, ARP-1, MM.1S, OPM-2, and RPMI 8226) revealed that tumorigenesis is associated with enhanced levels of the eukaryotic translation initiation factors 4E and gamma-1 (eIF4E and eIF4GI, respectively), which upregulate the translation of crucial oncogenes [78].