Five studies reported an association between the XRCC1 rs25487 G>A polymorphism and prognosis in HCC, 3 studies reported an association for XRCC1 rs1799782 C>T, 2 studies reported an association for ERCC2 rs13181 A>C, 3 studies reported an association for ERCC2 rs1799793 G>A, and 2 studies reported an association for XRCC3 rs861539 C>T (Table 1). This evidence concerns the gene XRCC1 and hepatocellular carcinoma.