XRCC3 and hepatocellular carcinoma: In 2012, Han et al. [10] found that individuals with XRCC3 CT (HR = 1.96, 95% CI = 1.23–3.15) and TT genotypes (HR = 2.98, 95% CI = 1.77–7.54) have a significantly higher risk of HCC than that of individuals with the XRCC3 CC genotype.