While IL-10−/− mice colonized with the SIHUMI consortium gradually developed inflammation in the distal colon (SIHUMI histopathological score: 3.1 ± 2.3), colitis severity was significantly increased when E. faecalis OG1RF was replaced by Δeut mutant strain (SIHUMI Δeut histopathological score: 6.1 ± 1.8) (Figures 2H, I). This evidence concerns the gene IL10 and colitis.