HMOX1 and neoplasm: As for expression analysis in the kidney, only JQC and JYH concocted LGT promoted Nrf2 nuclear aggregation in tumour mice, evidenced by significantly upregulated Nrf2 protein levels, and Nrf2 and HO-1 mRNA levels, suggesting that Nrf2 activation in kidney could probably participate in the JQC and JYH concocted detoxification mechanism of LGT.