The same was true after adjustment for age, sex, BMI and fibrinogen (Supplementary Table 3) as well as after additional adjustment for coronary artery disease, heart failure/left ventricular dysfunction, GFR, antiplasmin, PAI-1, TAFI, C-reactive protein (CRP) and cTnI-hs (Table 3). The gene discussed is SERPINE1; the disease is coronary artery disorder.