PTK6-overexpression increased cell survival in RWPE-2 (26.5%), PC3 (34.2%) & DU145 (67.8%), and MDA-PCa-2b (85.3%) cells compared with empty vector transfected cells (Fig. 4F, lower panel) suggesting that, PKT6 expression positively modulates cell survival in PCa cells. This evidence concerns the gene PTK6 and posterior cortical atrophy.