Furthermore, the same is also observed in primary tauopathies such as PiD, CBD, PSP, Guam Parkinson, Anti-IgLON5 disease [21, 56, 105, 106, 127, 128, 144, 237, 267], and tau transgenic animals [13, 140, 260, 289, 322, 331, 332]. The gene discussed is MAPT; the disease is supranuclear palsy, progressive, 1.