The most prevalent genetic causes of ALS are mutations in the genes encoding superoxide dismutase 1 (SOD1), TAR DNA-binding protein 43 (TDP-43) and fused in sarcoma (FUS), as well as hexanucleotide repeats in the ‘Chromosome 9 open reading frame 72’ (C9orf72) gene [2]. The gene discussed is SOD1; the disease is amyotrophic lateral sclerosis.