In the framework of this review, it could be worth to mention that CK2 is also implicated in key processes which lead to radio-resistance: inhibition of CK2 has been found to reduce the secretion of IL-8 and IL-6 by endothelial cells after ionizing radiation (IR), and proposed as a strategy to improve the IR outcomes in non-small cell lung cancer cells [124, 129]. The gene discussed is CXCL8; the disease is non-small cell lung carcinoma.