Among the loci studied, heterozygotes for the minor allele of H19 rs2839698 (T) and rs3741219 (G) were more inclined to have HCC with the OR being 1.291 (95% CI, 1.003–1.661; p = 0.047), and 1.361 (95% CI, 1.054–1.758; p = 0.018), respectively. The gene discussed is H19; the disease is hepatocellular carcinoma.