On the other hand, our network analysis showed that these AML cells had increased levels of several members of a signaling pathway, including cell surface integrins (αLβ2, αMβ2) known to mediate downstream signaling involving SYK and SRC kinase family members (FGR, HCK) [48,49,50,51]. The gene discussed is FGR; the disease is acute myeloid leukemia.