We have previously shown low expression of miR526b and miR655 in ER receptor positive cell lines MCF7 and T47D, and that these miRNA have the highest expression in triple negative breast cancer cells MDAMB231, MCF7-COX2, and Hs578T, with a relative correlation of miRNA expression with COX-2 expression [11]. The gene discussed is PTGS2; the disease is triple-negative breast carcinoma.