ERBB3 and glioblastoma: On the basis of the prevalent “seed and soil” theory, Pradeep et al. demonstrated the non-random pattern of hematogenous dissemination of ERBB3+ circulating OC cells, which preferably metastasize to omentum with high neuregulin1(NRG1) level [62]; ERBB3 was previously shown to enable glioblastoma CSC proliferation [121].