In a recent study examining the influence of BMI on cytokines in drug naive first-episode psychosis patients, IL-8 was the only cytokine increased in normal-weight patients compared to normal-weight controls [34], whereas over-weight patients had increased levels of IL-6, IL-8, CCL-4, IL-13, IL-2, IL-7, IL-12p70 and IL-23 compared to over-weight controls [34]. The gene discussed is CCL4; the disease is psychotic disorder.