JUP and Arrhythmogenic right ventricular dysplasia: At present, mutations in more than ten genes like plakophilin 2 (PKP2), desmoplakin (DSP), desmocollin 2 (DSC2), desmoglein 2 (DSG2), and junction plakoglobin (JUP) may be responsible for ARVC as have been reported [6, 7].