Depth of tumor invasion (p=0.025), lymph node metastasis (p<0.001), distant metastasis (p<0.001), tumor TNM stage (p<0.001), PD-L1-positive status in tumor (p=0.002, Figure 3(a)), and A2aR-positive status in tumor (p=0.017, Figure 3(b)) were significantly correlated to OS (p<0.05). Here, ADORA2A is linked to neoplasm.