This study has shown that in contrast to peanut allergy, in which sensitization to a specific peanut component (Ara h 2) predicts clinical reactivity (73), what predicted asthma was not IgE to any individual molecule, but the pattern of interaction between allergen component-specific IgEs (72) However, further research is required to establish whether IgE connectivity patterns can be used in diagnostic tools to facilitate asthma diagnosis in a clinical situation. This evidence concerns the gene IGHE and asthma.