IGHE and cystic fibrosis: Minimum Criteria: (1) patients with asthma or cystic fibrosis, (2) worsening lung function, (3) positive skin prick test with aspergillus species, (4) total serum IgE greater than 1000 ng/mL (416 IU/mL), (5) increased aspergillus species-specific IgE and IgG antibodies, (6) infiltrates noted on chest radiography