TMPRSS2 and cancer: However, in contrast to the analysis of PDE4D5 scores, the survival analysis of PDE4D9 score categories in gene fusion positive cancers resulted in a significant association with biochemical recurrence, although with a somewhat weaker p compared to the TMPRSS2-ERG negative tumours (logrank p=0.005 vs. logrank p<0.0001, respectively; Figures 1(e) and 1(f)).