In a recent study, Liu et al. found that GAS5 is downregulated in CRC tissues, plasma, and exosomes, with an AUC for tissue GAS5 levels distinguishing CRC and NATs of 0.791 and GAS5 in plasma and exosomes distinguishing 158 patients with CRC and 173 healthy subjects with AUC values of 0.875 and 0.964, respectively [76]. The gene discussed is GAS5; the disease is colorectal carcinoma.