NFE2L2 and metabolic dysfunction-associated steatotic liver disease: Interestingly, specific co-recruitment of Phf2 and ChREBP to the promoter of nuclear factor erythroid 2 like 2 (Nrf2) contributes to the protective effect of Phf2 against increased reactive oxygen species (ROS) and NAFLD progression in the context of hyperglycemia (Bricambert et al., 2018).