FUT4 and colon adenoma: Figure 5 shows two patients with premalignant colonic adenomas. One had 4% MDSC (CD15+) in PBMC (Figures 5A,B) and the other had 31% (Figures 5C,D). In the case of low to normal numbers of MDSC (4%), T cell proliferation rate was the same in whole PBMC (Figure 5A) and after MDSC depletion (Figure 5B). On the other hand, in the setting of high MDSC levels (31%), proliferation of T cells was inhibited in whole PBMC (Figure 5C) but restored after CD15+ cell depletion (Figure 5D).