Indeed, while all inhibitors apart from probucol dose-dependently decreased IL-1β release upon nga(G330D) infection, secretion upon ATP-driven inflammasome activation was reduced by glyburide, DIDS and probucol (Figures 5C,D,G; right panels), unaffected by BLT-4 (Figure 5E, right panel) and increased in the presence of vanadate (Figure 5F, right panel). The gene discussed is IL1B; the disease is infection.