CD4 and melanoma: Still, when we divided patients into two groups by the mean age, the TCR data did not show statistically significant differences between younger and older melanoma patients in our analyses (Figure 2A, CD4, Restricted Vβ-gene families, p = 0.47; CD4, Distinct peaks, p = 0.55; CD8, Restricted Vβ-gene families, p = 0.52; CD8, Distinct peaks, p = 0.62).