FRET analysis showed that HAS3 interacted with TUBB3, which is a neuroblastoma cell‐specific marker of differentiation (Figure 2C).29 These results demonstrate that overexpressing HAS3 either by serum deprivation (Figure 1) or by transfection with an HAS3 plasmid (Figure 2) triggers significant differentiation in N2a cells, as evidenced by increases in neuron length and related markers of differentiation. This evidence concerns the gene TUBB3 and neuroblastoma.