STAT3 and neoplasm: Our previous studies have shown that quercetin could protect the liver from concanavalin A‐induced acute hepatitis, ischemia reperfusion injury, and fibrosis.11, 12, 13 Others have reported that quercetin had effective anticancer functions in hepatocellular carcinoma1, 6, 14, 15 and this function may have a close relationship with the STAT3 pathway.8, 16, 17, 18 As a cytokine, the transcription factor STAT3, has been testified that it is closely associated with tumor development.