PYGO2 and breast carcinoma: Multiple reports have demonstrated the role of miRNAs in the breast cancer metastasis.19, 30, 31, 32 In this study, the results demonstrate that miR‐516a‐3p inhibits breast cancer cells growth, metastasis and EMT by suppressing the Pygo2/Wnt/β‐catenin signalling pathway (Figure 7G).