BRCA1 and neoplasm: Similar lesions are induced by DNA‐alkylating agents (Fu et al, 2012), which include mono‐functional (e.g. mitomycin C, nimustine) or bifunctional alkylators (e.g. chlorambucil, cyclophosphamide, melphalan), some showing specific toxicity against BRCA1/2‐deficient cells and tumours (Evers et al, 2010; Vollebergh et al, 2014; Pajic et al, 2017).