TGFB1 and Hepatic fibrosis: During the fibrotic process, TGF‐β1 is the key regulating cytokine, and was reported to have essential impact on liver fibrosis.23 In TGF‐β1 signalling, Smads proteins are major mediators via receptor‐induced phosphorylation and nuclear translocation.24 Based on these findings, we next investigated the TGF‐β1/Smads pathway.