Moreover, van Vlodrop et al. (2017) demonstrate that the four gene promoters composed of Gremlin 1, DAN Family BMP Antagonist, neuralized E3 ubiquitin protein ligase 1, Ladinin 1, and neurofilament heavy can be used as prognostic markers of ccRCC. Here, LAD1 is linked to nonpapillary renal cell carcinoma.