CYTIP and nonpapillary renal cell carcinoma: And so far, only one methylation‐driven genes, Cytohesin 1 Interacting protein, has been reported to have an effect on ccRCC in previous studies, and the paper concludes that hypermethylation of this driver gene may be a feature of good prognosis in KIRC (Gevaert, Tibshirani, & Plevritis, 2015).