Notably, in that work, the authors showed that bacterial curli fibers triggered T-cell immunity through the TLR-2-MyD88-NF-kB signaling pathway, which is also known to be associated with T1D progression; however, no microbiome studies have been conducted to reveal the association of amyloid-producing bacteria with diabetes36. The gene discussed is TLR2; the disease is type 1 diabetes mellitus.