Interferon-inducible Transmembrane Protein 3 (IFITM3) is a member of the IFITM gene family that acts as a key role in immune cell signaling, cell adhesion, and stem cell migration7,8, which is involved in regulating primal germ cell migration, hepatitis C virus infection, and endodermal localization, as well as mediating the regulation of endothelial cells, adhesion, and apoptosis of leukocytes and other biological processes9–11. Here, IFITM3 is linked to hepatitis C virus infection.