EZH2 and colorectal carcinoma: Currently, EPHA7 was validated to be involved in SNHG14-regulated CRC progression, and the negative regulation of SNHG14 on EPHA7 was disclosed to be mediated by EZH2 via modulating the methylation of EPHA7 promoter, consistent with a previous finding that EPHA7 downregulation in CRC is due to its hypermethylation30.