In contrast, compared with the normal human colonic cell line NCM460, we observed that the level of SNHG14 was distinctly enhanced in all the five CRC cell lines including HT-29, SW620, SW480, HCT-116, and LoVo, among which LoVo cells exhibited the highest endogenous SNHG14 expression while HT-29 cells showed the lowest conversely (Fig. 1b). Here, SNHG14 is linked to colorectal carcinoma.