HIF1A and cancer: To further reveal the potential mechanism of the anti-cancer effect of Wumei Pill on pancreatic neoplasms, we conducted KEGG pathway enrichment analysis on 77 targets and screened out 17 pathways based on the threshold of FDR<0.01 and cancer-related signaling pathways, for instance, TNF signaling pathway (hsa04668), HIF-1 signaling pathway (hsa04066), Apoptosis (hsa04210), p53 signaling pathway (hsa04115), PI3K-Akt signaling pathway (hsa04151), VEGF signaling pathway (hsa04370), NF-kappa B signaling pathway (hsa04064), etc.(Table 2).